Mentioning it is one of the easiest ways to get people to throw personal anecdotes at you like they’re scientific evidence. MSG’s bad reputation began in the late 1960s, when the author of a letter to the editor of The New England Journal of Medicine complained of what he called “Chinese restaurant syndrome” — numbness, weakness, and headaches, all of which he attributed to the MSG in Chinese food. But decades of research have found no link between MSG and weakness, numbness, or headaches in most people.
The Smithsonian’s recent article on MSG: “It’s the Umami, Stupid. Why the Truth About MSG is So Easy to Swallow”